Publications

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In Press
Beguerisse-Díaz M, Bosque G, Oyarzún D, Picó J, Barahona M.  In Press.  Flux-dependent graphs for metabolic networks. Nature Systems Biology and Applications.
2017
Boada Y, Vignoni A, Picó J.  2017.  Engineered control of genetic variability reveals interplay between quorum sensing, feedback regulation and biochemical noise. ACS Synthetic Biology.
De Battista H, Jamilis M, Garelli F, Picó J.  2017.  Global stabilisation of continuous bioreactors: tools for analysis and design of feeding laws. Automatica.
2016
Picó-Marco E, Boada Y, Picó J, Vignoni A.  2016.  Contractivity of a genetic circuit with internal feedback and cell-to-cell communication. IFAC-PapersOnLine . 49 (26):218.
Boada Y, Pitarch JL, Vignoni A, Reynoso-Meza G, Picó J.  2016.  Optimization Alternatives for Robust Model-based Design of Synthetic Biological Circuits. FAC-PapersOnLine . 49(7):826.
Boada Y, Vignoni A, Reynoso-Meza G, Picó J.  2016.  Parameter identification in synthetic biological circuits using multi-objective optimization. IFAC-PapersOnLine. 49(26):82.
Reynoso-Meza G, Carrillo-Ahumada J, Boada Y, Picó J.  2016.  PID controller tuning for unstable processes using a multi-objective optimisation design procedure. IFAC-PapersOnLine . 49(7):289.
2015
Folch-Fortuny A, Tortajada M, Prats-Montalbán JM, Llaneras F, Picó J, Ferrer A.  2015.  MCR-ALS on metabolic networks: Obtaining more meaningful pathways. Chemometrics and Intelligent Laboratory Systems. 142:293-303.
2014
Nuñez S, De Battista H, Garelli F, Picó J.  2014.  Sufficient conditions for state observability in multi-substrate bioprocesses with additive growth dynamics. IEEE Latin America Transactions. 12(5)
Bosque G, Folch-Fortuny A, Picó J, Ferrer A, Elena S.F.  2014.  Topology analysis and visualization of Potyvirus protein-protein interaction network. BMC Systems Biology. 8(1)
2013
Vignoni A, Garelli F, Picó J.  2013.  Coordinación de sistemas con diferentes dinámicas utilizando conceptos de invarianza geométrica y modos deslizantes.. Revista Iberoamericana de Automática e Informática industrial. 10(4):390-401.
Revert A, Garelli F, Picó J, De Battista H, Rossetti P, Vehi J, Bondia J.  2013.  Safety Auxiliary Feedback Element for the Artificial Pancreas in Type 1 Diabetes. IEEE Trans. on Biomedical Engineering. 60(8):2113-2122.
Nuñez S, De Battista H, Garelli F, Vignoni A, Picó J.  2013.  Second-Order Sliding Mode Observer for Multiple Kinetic Rates Estimation in Bioprocesses. Control Engineering Practice. 21(9):1259-1265.
Picó J, Picó–Marco E, Vignoni A, De Battista H.  2013.  Stability preserving maps for finite-time convergence: super-twisting sliding-mode algorithm. Automatica. 49(2):539.
2012
Llaneras F, Sala A., Picó J.  2012.  Dynamic estimations of metabolic fluxes with constraint-based models and possibility theory. Journal of Process Control. 22
Tortajada M, Llaneras F, Ramón D, Picó J.  2012.  Estimation of recombinant protein production in Pichia pastoris based on a constraint-based model. Journal of Process Control. :-.
De Battista H, Picó J, Picó-Marco E.  2012.  Nonlinear PI control of fed-batch processes for growth rate regulation. Journal of Process Control. 22:789-797.
Vignoni A, Oyarzún D, Picó J, Stan G-B.  2012.  Population-level control of heterologous protein production in bacteria. Applied Synthetic Biology in Europe Programme.
De Battista H, Picó J, Garelli F, Navarro J.  2012.  Reaction rate reconstruction from biomass concentration measurement in bioreactors using modified second-order sliding mode algorithms. Bioprocess and Biosystems Engineering. :1-11.
Vignoni A, Picó J, Garelli F, De Battista H.  2012.  Sliding mode reference conditioning for coordination in swarms of non-identical multi-agent systems. Variable Structure Systems (VSS), 2012 12th International Workshop on.
2011
Vignoni A, Picó J, Garelli F, De Battista H.  2011.  Dynamical Systems Coordination Via Sliding Mode Reference Conditioning. 18th IFAC World Congress.
De Battista H, Picó J, Garelli F, Vignoni A.  2011.  Specific growth rate estimation in (fed-)batch bioreactors using second-order sliding observers. Journal of Process Control. 21:1049–1055.
2010
Llaneras F, Sala A., Picó J.  2010.  Possibilistic Estimation of Metabolic Fluxes During a Batch Process Accounting for Extracellular Dynamics. 11
Tortajada M, Llaneras F, Picó J.  2010.  Validation of a constraint-based model of Pichia pastoris metabolism under data scarcity.. BMC Systems Biology. 4:115.
Llaneras F, Picó J.  2010.  Which metabolic pathways generate and characterize the flux space? A comparison among elementary modes, extreme pathways and minimal generators. Journal of Biomedicine and Biotechnology. 2010:753904.

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