Publications

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Journal Article
Llaneras F, Picó J.  2010.  Which metabolic pathways generate and characterize the flux space? A comparison among elementary modes, extreme pathways and minimal generators. Journal of Biomedicine and Biotechnology. 2010:753904.
Tortajada M, Llaneras F, Picó J.  2010.  Validation of a constraint-based model of Pichia pastoris metabolism under data scarcity.. BMC Systems Biology. 4:115.
Llaneras F, Picó J.  2008.  Stoichiometric modelling of cell metabolism.. Journal of bioscience and bioengineering. 105:1–11.
Picó J, Picó–Marco E, Vignoni A, De Battista H.  2013.  Stability preserving maps for finite-time convergence: super-twisting sliding-mode algorithm. Automatica. 49(2):539.
De Battista H, Picó J, Garelli F, Vignoni A.  2011.  Specific growth rate estimation in (fed-)batch bioreactors using second-order sliding observers. Journal of Process Control. 21:1049–1055.
Picó J, De Battista H, Garelli F.  2009.  Smooth sliding-mode observers for specific growth rate and substrate from biomass measurement. Journal of Process Control.
Picó-Marco E, Picó J, De Battista H.  2005.  Sliding mode scheme for adaptive specific growth rate control in biotechnological fed-batch processes. International Journal of Control. 78:128–141.
Camacho J, Picó J, Ferrer A.  2007.  Self-tuning run to run optimization of fed-batch processes using unfold-PLS. AIChE journal.
Nuñez S, De Battista H, Garelli F, Vignoni A, Picó J.  2013.  Second-Order Sliding Mode Observer for Multiple Kinetic Rates Estimation in Bioprocesses. Control Engineering Practice. 21(9):1259-1265.
Revert A, Garelli F, Picó J, De Battista H, Rossetti P, Vehi J, Bondia J.  2013.  Safety Auxiliary Feedback Element for the Artificial Pancreas in Type 1 Diabetes. IEEE Trans. on Biomedical Engineering. 60(8):2113-2122.
De Battista H, Picó J, Garelli F, Navarro J.  2012.  Reaction rate reconstruction from biomass concentration measurement in bioreactors using modified second-order sliding mode algorithms. Bioprocess and Biosystems Engineering. :1-11.
Llaneras F, Picó J.  2007.  A procedure for the estimation over time of metabolic fluxes in scenarios where measurements are uncertain and/or insufficient. BMC bioinformatics.
Llaneras F, Sala A., Picó J.  2009.  A possibilistic framework for constraint-based metabolic flux analysis. BMC Systems Biology. 3
De Battista H, Picó J, Picó-Marco E.  2012.  Nonlinear PI control of fed-batch processes for growth rate regulation. Journal of Process Control. 22:789-797.
Camacho J, Picó J.  2006.  Multi-phase principal component analysis for batch processes modelling. Chemometrics and intelligent laboratory systems.
Camacho J, Picó J, Ferrer A.  2008.  Multi-phase analysis framework for handling batch process data. Journal of Chemometrics. 22:632–643.
Picó J, Sanchez A, Bondia J, Escudero D, Torregrosa A, Correcher C.  2005.  Intelligent Robotic Cell for Trencad&\#205;s Mosaics Manufacturing}. IEEE Transactions on Systems, Man and Cybernetics, Part C (Applications and Reviews). 35:75–86.
De Battista H, Picó J, Picó-Marco E.  2006.  Globally stabilizing control of fed-batch processes with Haldane kinetics using growth rate estimation feedback. Journal of Process Control. 16:865–875.
Picó J, Garelli F, De Battista H, Mantz R.  2009.  Geometric invariance and reference conditioning ideas for control of overflow metabolism. Journal of Process Control. 19:1617–1626.
De Battista H, Picó-Marco E, Picó J.  2005.  On `Feedback stabilization of fed-batch bioreactors: non-monotonic growth kinetics'. Biotechnology progress. 21:651–652.
Tortajada M, Llaneras F, Ramón D, Picó J.  2012.  Estimation of recombinant protein production in Pichia pastoris based on a constraint-based model. Journal of Process Control. :-.
Llaneras F, Sala A., Picó J.  2012.  Dynamic estimations of metabolic fluxes with constraint-based models and possibility theory. Journal of Process Control. 22
Vignoni A, Garelli F, Picó J.  2013.  Coordinación de sistemas con diferentes dinámicas utilizando conceptos de invarianza geométrica y modos deslizantes.. Revista Iberoamericana de Automática e Informática industrial. 10(4):390-401.
Bondia J, Sala A., Picó J, Sainz MA.  2006.  Controller Design Under Fuzzy Pole-Placement Specifications: An Interval Arithmetic Approach. Fuzzy Systems, IEEE Transactions on. 14:822–836.
Tarin C, Teufel E, Picó J, Bondia J, Pfleiderer HJ.  2005.  Comprehensive Pharmacokinetic Model of Insulin Glargine and Other Insulin Formulations. IEEE Transactions on Biomedical Engineering. 52:1994–2005.

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