2025
Sensitivity of inducible gene expression Proceedings Article
En: # PLACEHOLDER_PARENT_METADATA_VALUE#, pp. 33–34, 2025.
2024
DBTL bioengineering cycle for part characterization and refactoring Artículo de revista
En: IFAC-PapersOnLine, vol. 58, no 23, pp. 7–12, 2024.
Mini-bioreactor for parts characterization of a biological circuit: Absorbance and Fluorescence measurement calibration, and online growth rate estimation Artículo de revista
En: IFAC-PapersOnLine, vol. 58, no 23, pp. 97–102, 2024.
Towards Constraint-Based Burden-Aware Models for Metabolic Engineering Artículo de revista
En: IFAC-PapersOnLine, vol. 58, no 14, pp. 247–252, 2024.
2023
PLATERO: a calibration protocol for plate reader green fluorescence measurements Artículo de revista
En: Frontiers in Bioengineering and Biotechnology, vol. 11, pp. 1104445, 2023.
Towards automation of the design-build-test-learn (dbtl) bioengineering cycle: Application to the testing and characterization of standard bioparts Artículo de revista
En: XLIV Jornadas de Automática, pp. 453–458, 2023.
2022
Modeling and optimization of a molecular biocontroller for the regulation of complex metabolic pathways Artículo de revista
En: Frontiers in Molecular Biosciences, vol. 9, pp. 801032, 2022.
Onemodel: an open-source sbml modeling tool focused on accessibility, simplicity and modularity Artículo de revista
En: IFAC-PapersOnLine, vol. 55, no 7, pp. 125–130, 2022.
Optimization of the dynamic regulation in a branch-in metabolic pathway Artículo de revista
En: IFAC-PapersOnLine, vol. 55, no 7, pp. 119–124, 2022.
2021
Gene expression space shapes the bioprocess trade-offs among titer, yield and productivity Artículo de revista
En: Applied Sciences, vol. 11, no 13, pp. 5859, 2021.
Gene variant space for biosensor-based dynamic regulation Proceedings Article
En: XLII Jornadas de Automática: libro de actas, Castellón, 1 a 3 de septiembre de 2021, pp. 485–491, Universitat Jaume I 2021.
Gene variant space for biosensor-based dynamic regulation Proceedings Article
En: XLII Jornadas de Automática, pp. 485–498, Universidade da Coruña, Servizo de Publicacións 2021.
Multi-objective optimization tuning framework for kinetic parameter selection and estimation Book Section
En: Computational Methods for Estimating the Kinetic Parameters of Biological Systems, pp. 65–89, Springer US New York, NY, 2021.
RBS and promoter strengths determine the cell-growth-dependent protein mass fractions and their optimal synthesis rates Artículo de revista
En: ACS synthetic biology, vol. 10, no 12, pp. 3290–3303, 2021.
Stochastic differential equations for practical simulation of gene circuits Artículo de revista
En: Synthetic Gene Circuits: Methods and Protocols, pp. 41–90, 2021.
2020
Extended metabolic biosensor design for dynamic pathway regulation of cell factories Artículo de revista
En: Iscience, vol. 23, no 7, 2020.
Resources allocation explains the differential roles of RBS and promoter strengths in cell mass distribution and optimal protein expression productivity Artículo de revista
En: bioRxiv, pp. 2020–11, 2020.
2019
Analysis of transcriptional feedback strategy for reducing interaction in gene expression processes Artículo de revista
En: IFAC-PapersOnLine, vol. 52, no 1, pp. 526–531, 2019.
Batch Processes: Monitoring and Process Understanding–Latent Structure Based Methods Miscelánea
2019.
Biomolecular signal tracker with fast time response. Artículo de revista
En: IFAC-PapersOnLine, vol. 52, no 26, pp. 1–6, 2019.
Characterization of gene circuit parts based on multiobjective optimization by using standard calibrated measurements Artículo de revista
En: ChemBioChem, vol. 20, no 20, pp. 2653–2665, 2019.
Fluorescence calibration and color equivalence for quantitative synthetic biology. Artículo de revista
En: IFAC-PapersOnLine, vol. 52, no 26, pp. 129–134, 2019.
Multiobjective identification of a feedback synthetic gene circuit Artículo de revista
En: IEEE Transactions on Control Systems Technology, vol. 28, no 1, pp. 208–223, 2019.
Reference conditioning anti-windup for the biomolecular antithetic controller Artículo de revista
En: IFAC-PapersOnLine, vol. 52, no 26, pp. 156–162, 2019.
2018
Flux-dependent graphs for metabolic networks Artículo de revista
En: NPJ systems biology and applications, vol. 4, no 1, pp. 32, 2018.
Global stabilisation of continuous bioreactors: Tools for analysis and design of feeding laws Artículo de revista
En: Automatica, vol. 89, pp. 340–348, 2018.
Host-circuit interactions explain unexpected behavior of a gene circuit. Artículo de revista
En: IFAC-PapersOnLine, vol. 51, no 19, pp. 86–89, 2018.
Output feedback linearization of turbidostats after time scaling Artículo de revista
En: IEEE Transactions on Control Systems Technology, vol. 27, no 4, pp. 1668–1676, 2018.
2017
Engineered control of genetic variability reveals interplay among quorum sensing, feedback regulation, and biochemical noise Artículo de revista
En: ACS synthetic biology, vol. 6, no 10, pp. 1903–1912, 2017.
Multi-objective identification of synthetic circuits stochastic models using flow flcytometry data Proceedings Article
En: 2017 25th Mediterranean Conference on Control and Automation (MED), pp. 1077–1082, IEEE 2017.
Multi-objective optimization for gene expression noise reduction in a synthetic gene circuit Artículo de revista
En: IFAC-PapersOnLine, vol. 50, no 1, pp. 4472–4477, 2017.
Promoter and transcription factor dynamics tune protein mean and noise strength in a quorum sensing-based feedback synthetic circuit Artículo de revista
En: bioRxiv, pp. 106229, 2017.
Reduction of population variability in protein expression: A control engineering approach Artículo de revista
En: Actas de las XXXVIII Jornadas de Automática, 2017.
2016
Context-dependent metabolic networks Artículo de revista
En: arXiv preprint arXiv:1605.01639, 2016.
Contractivity of a genetic circuit with internal feedback and cell-to-cell communication Artículo de revista
En: Ifac-Papersonline, vol. 49, no 26, pp. 213–218, 2016.
Fusion of genomic, proteomic and phenotypic data: The case of potyviruses Artículo de revista
En: Molecular BioSystems, vol. 12, no 1, pp. 253–261, 2016.
Multi-objective optimization framework to obtain model-based guidelines for tuning biological synthetic devices: an adaptive network case Artículo de revista
En: BMC systems biology, vol. 10, pp. 1–19, 2016.
Optimization alternatives for robust model-based design of synthetic biological circuits Artículo de revista
En: Ifac-Papersonline, vol. 49, no 7, pp. 821–826, 2016.
Parameter identification in synthetic biological circuits using multi-objective optimization Artículo de revista
En: Ifac-Papersonline, vol. 49, no 26, pp. 77–82, 2016.
PFA toolbox: a MATLAB tool for Metabolic Flux Analysis Artículo de revista
En: BMC systems biology, vol. 10, pp. 1–10, 2016.
PID controller tuning for unstable processes using a multi-objective optimisation design procedure Artículo de revista
En: IFAC-PapersOnLine, vol. 49, no 7, pp. 284–289, 2016.
2015
Improvement of a cle stochastic simulation of gene synthetic network with quorum sensing and feedback in a cell population Proceedings Article
En: 2015 European Control Conference (ECC), pp. 2274–2279, IEEE 2015.
MCR-ALS on metabolic networks: Obtaining more meaningful pathways Artículo de revista
En: Chemometrics and Intelligent Laboratory Systems, vol. 142, pp. 293–303, 2015.
Modelado de sistemas bioqu'ımicos: De la ley de acción de masas a la aproximación lineal del ruido Artículo de revista
En: Revista Iberoamericana de Automática e Informática Industrial RIAI, vol. 12, no 3, pp. 241–252, 2015.
Modelling biochemical systems: from mass action kinetics to linear noise approximation Artículo de revista
En: REVISTA IBEROAMERICANA DE AUTOMATICA E INFORMATICA INDUSTRIAL, vol. 12, no 3, pp. 241–252, 2015.
2014
Alternativas de biologıa sintética para el control de rutas metabólicas Artículo de revista
En: 2014.
Diseno de control no lineal para regulación de tasa de crecimiento en cultivos multi-sustrato Artículo de revista
En: Actas de las XXXV Jornadas de Automática, Espana, 2014.
Metabolic flux understanding of Pichia pastoris grown on heterogenous culture media Artículo de revista
En: Chemometrics and Intelligent Laboratory Systems, vol. 134, pp. 89–99, 2014.
Sufficient conditions for state observability in multi-substrate bioprocesses with additive growth dynamics Artículo de revista
En: IEEE Latin America Transactions, vol. 12, no 5, pp. 928–934, 2014.
Topology analysis and visualization of Potyvirus protein-protein interaction network Artículo de revista
En: BMC systems biology, vol. 8, pp. 1–15, 2014.
