sb2cl Lab

The Synthetic Biology and Biosystems Control Lab (SB2CL) forms part of the Control of Complex Systems Group within the Institute for Automatica and Industrial Informatics(ai2) at the Technical University of Valencia(Spain). The SB2C Lab focuses its research on applications of systems engineering and control to Systems and Synthetic Biology, and Bioprocesses estimation and control.  

Our main interests are in:

  • Synthetic genetic circuits for control of cell population variability, and control of intracelullar metabolites

  • Multi-criteria optimization-based tuning of synthetic genetic circuits

  • Analysis of metabolic networks, and possibilistic methods for Metabolic Flux Analysis and Flux Balance Analysis

  • Control of specific growth rate and concentration in  bioreactors

  • Sliding-mode observers for specific growth rate in  bioreactors